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1

Comparative evaluation of acute cerebral vasospasm by the microsphere and the angiography techniques

Sébastien Roux, Martine Clozel, Robert Wolfgang, Urs Sprecher, Jean Paul Clozel

Journal:

Journal of Neuroscience Methods

Year:

1995

Language:

english

File:

PDF, 2.28 MB

english, 1995

2

Blockade of receptor-operated calcium channels by mibefradil (Ro 40-5967): Effects on intracellular calcium and platelet aggregation

Martina Hahn, Vsevolod A. Tkachuk, Valery N. Bochkov, Ivan B. Cheglakov, Jean-Paul Clozel

Journal:

Cardiovascular Drugs and Therapy

Year:

1995

Language:

english

File:

PDF, 679 KB

english, 1995

3

The structurally novel Ca2+channel blocker Ro 40-5967, which binds to the [3H] desmethoxyverapamil receptor, is devoid of the negative inotropic effects of verapamil in normal and failing rat hearts

Jean-Paul Clozel, Murielle Véniant, Wolfgang Osterrieder

Journal:

Cardiovascular Drugs and Therapy

Year:

1990

Language:

english

File:

PDF, 470 KB

english, 1990

4

Ro 40–5967: A New Nondihydropyridine Calcium Antagonist

Jean-Paul Clozel, Wolfgang Osterrieder, Cornells H. Kleinbloesem, Horst A. Welker, Bernhard Schläppi, Robert Tudor, Fridolin Hefti, Rita Schmitt, Herwig Eggers

Journal:

Cardiovascular Therapeutics

Year:

1991

Language:

english

File:

PDF, 791 KB

english, 1991

5

Calcium blockade versus ACE inhibition in clipped and unclipped kidneys of 2K-1C rats

Véniant, Murielle, Heudes, Didier, Clozel, Jean-Paul, Bruneval, Patrick, Ménard, Joël

Journal:

Kidney International

Year:

1994

Language:

english

File:

PDF, 877 KB

english, 1994

6

T-Type Ca2+Channels and Pharmacological Blockade: Potential Pathophysiological Relevance

Sylvie I. Ertel, Eric A. Ertel, Jean-Paul Clozel

Journal:

Cardiovascular Drugs and Therapy

Year:

1997

Language:

english

File:

PDF, 364 KB

english, 1997

7

Cardiovascular alterations in rat fetuses exposed to calcium channel blockers

William J. Scott Jr., Elisabeth Resnick, Hans Hummler, Jean-paul Clozel, Heinrich Bürgin

Journal:

Reproductive Toxicology

Year:

1997

Language:

english

File:

PDF, 807 KB

english, 1997

8

Influence of Congestive Heart Failure on Endothelin Levels and Receptors in Rabbits

Bernd-Michael Löffler, Sébastien Roux, Barbara Kalina, Martine Clozel, Jean-Paul Clozel

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1993

File:

PDF, 372 KB

1993

9

Duration of improved exercise performance following oral diltiazem in chronic stable angina

Pierre Wagniart, Bernard R. Chaitman, Ronald J. Ferguson, Geneviève Brévers, Jean-Marie Scholl, Jean-Paul Clozel, André Pasternac, Martial G. Bourassa

Journal:

The American Journal of Cardiology

Year:

1982

Language:

english

File:

PDF, 166 KB

english, 1982

10

Role of endothelin in mediating neurogenic plasma extravasation in rat dura mater

Peter Brändli, Bernd-Michael Löffler, Volker Breu, Rolf Osterwalder, Jean-Paul Maire, Martine Clozel

Journal:

Year:

1996

Language:

english

File:

PDF, 866 KB

english, 1996

11

Respective role of humoral factors and blood pressure in aortic remodeling of DOCA hypertensive rats

Habib Karam, Didier Heudes, Marie-Françoise Gonzales, Bernd-Michael Löffler, Martine Clozel, Jean-Paul Clozel

Journal:

American Journal of Hypertension

Year:

1996

Language:

english

File:

PDF, 963 KB

english, 1996

12

Decreases of vascular hypertrophy in four different types of arteries in spontaneously hypertensive rats

Jean-Paul Clozel, Herbert Kuhn, Fridolin Hefti

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 708 KB

english, 1989

13

T channels and L channels: does it make a difference?

Jean-Paul Clozel

Journal:

American Journal of Hypertension

Year:

1998

Language:

english

File:

PDF, 129 KB

english, 1998

14

Major role of the renin angiotensin system in the neointima formation after vascular injury in guinea pigs

Jean-Paul Clozel, Patrick Hess, Käthi Schietinger, Volker Breu, Walter Fischli, Hans-Rudolf Baumgartner

Journal:

Year:

1994

Language:

english

File:

PDF, 420 KB

english, 1994

15

Endothelin plays a role in the maintenance of blood pressure in normotensive guinea pigs

Murielle Véniant, Jean-Paul Clozel, Patrick Hess, Martine Clozel

Journal:

Year:

1994

Language:

english

File:

PDF, 462 KB

english, 1994

16

Aprotinin: An antidote for recombinant tissue-type plasminogen activator (rt-PA) active in vivo

Jean-Paul Clozel, Ludger Banken, Sebastien Roux

Journal:

Journal of the American College of Cardiology

Year:

1990

Language:

english

File:

PDF, 223 KB

english, 1990

17

Increased Survival After Long-Term Treatment With Mibefradil, a Selective T-Channel Calcium Antagonist, in Heart Failure

Paul Mulder, PhD, Vincent Richard, PhD, Patricia Compagnon, Jean-Paul Henry, Françoise Lallemand, Jean-Paul Clozel, Robert Koen, Bertrand Macé, Christian Thuillez

Journal:

Journal of the American College of Cardiology

Year:

1997

Language:

english

File:

PDF, 220 KB

english, 1997

18

Temporal evolution of endothelial dysfunction in a rat model of chronic heart failure

John R. Teerlink, Martine Clozel, Walter Fischli, Jean-Paul Clozel

Journal:

Journal of the American College of Cardiology

Year:

1993

Language:

english

File:

PDF, 779 KB

english, 1993

19

Ca2+-agonistic effect of a novel cardiovascular drug mibefradil (Ro 40-5967)

Pavel V. Avdonin, Ivan B. Chegalakov, Vera P. Krymskaya, Vsevolod A. Tkachuk, Jean-Paul Clozel

Journal:

Pharmacological Research

Year:

1995

Language:

english

File:

PDF, 156 KB

english, 1995

20

Short-term endothelin receptor blockade with tezosentan has both immediate and long-term beneficial effects in rats with myocardial infarction

Martine Clozel, Changbin Qiu, Chang-Shen Qiu, Patrick Hess, Jean-Paul Clozel

Journal:

Journal of the American College of Cardiology

Year:

2002

Language:

english

File:

PDF, 177 KB

english, 2002

21

Vascular Protection with Cilazapril

Clozel, Jean Paul, Powell, Jerry S., Kuhn, Herbert, Müller, Rita K.M., Hefti, Fridolin, Baumgartner, Hans Rudolf

Journal:

Year:

1991

Language:

english

File:

PDF, 1.11 MB

english, 1991

22

Mibefradil (Ro 40-5967): the first selective T-type Ca2+ channel blocker

Ertel, Sylvie I, Clozel, Jean-Paul

Journal:

Expert Opinion on Investigational Drugs

Year:

1997

Language:

english

File:

PDF, 330 KB

english, 1997

23

Influence of hypoxemia and respiratory acidosis on the plasma kinetics and tissue distribution of digoxin in the conscious dog

Souich, Patrick Du, Clozel, Jean-Paul, Saunier, Claude, Ong, Huy, Hartemann, Denise, Garcia-Carmona, Teresa, Sadoul, Paul

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1985

Language:

english

File:

PDF, 751 KB

english, 1985

24

Chronic Treatment with the CA 2+ Channel Inhibitor RO 40-5967 Potentiates Endothelium-Dependent Relaxations in the Aorta of the Hypertensive Salt Sensitive Dahl Rat

Boulanger, Chantal M., Desta, Barnabas, Clozel, Jean-Paul, Vanhoutte, Paul M.

Journal:

Year:

1994

Language:

english

File:

PDF, 389 KB

english, 1994

25

Effects of diltiazem on atrioventricular conduction and arterial blood pressure: correlation with plasma drug concentrations

Clozel, Jean-Paul, Billette, Jacques, Caillé, Gilles, Théroux, Pierre, Cartier, Richard

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1984

Language:

english

File:

PDF, 1.03 MB

english, 1984

26

Respiratory Acidemia and Theophylline Pharmacokinetics in the Awake Dog

Clozel, Jean-Paul, Saunier, Claude, Royer-Morot, Marie-José, Royer, René J., Sadoul, Paul

Journal:

Year:

1981

Language:

english

File:

PDF, 628 KB

english, 1981

27

Effects of Nitrendipine and Cilazapril Alone or in Combination on Hemodynamics and Regional Blood Flows in Conscious Spontaneously Hypertensive Rats

Clozel, Jean-Paul

Journal:

Journal of Cardiovascular Pharmacology

Year:

1988

File:

PDF, 570 KB

1988

28

Cilazapril Prevents the Development of Cardiac Hypertrophy and the Decrease of Coronary Vascular Reserve in Spontaneously Hypertensive Rats

Clozel, Jean-Paul, Hefti, Fridolin

Journal:

Journal of Cardiovascular Pharmacology

Year:

1988

File:

PDF, 2.56 MB

1988

29

Effects of Ro 40-5967, a Novel Calcium Antagonist, on Myocardial Function During Ischemia Induced by Lowering Coronary Perfusion Pressure in Dogs: Comparison with Verapamil

Clozel, Jean-Paul, Banken, Ludger, Osterrieder, Wolfgang

Journal:

Journal of Cardiovascular Pharmacology

Year:

1989

File:

PDF, 88 KB

1989

30

Acute Hemodynamic Effects of Ciprokiren, a Novel Renin Inhibitor, in Sodium-Depleted Dogs

Clozel, Jean-Paul, Véniant, Murielle, Sprecher, Urs, Fischli, Walter

Journal:

Journal of Cardiovascular Pharmacology

Year:

1995

File:

PDF, 298 KB

1995

31

Effects of Ro 40–5967, a New Calcium Antagonist, and Enalapril on Cardiac Remodeling in Renal Hypertensive Rats

Véniant, Murielle, Clozel, Jean-Paul, Heudes, Didier, Banken, Ludger, Ménard, Joël

Journal:

Journal of Cardiovascular Pharmacology

Year:

1993

File:

PDF, 809 KB

1993

32

Combination of Low-Dose Valsartan and Enalapril Improves Endothelial Dysfunction and Coronary Reserve in Nω-Nitro-l-Arginine Methyl Ester–Treated Spontaneously Hypertensive Rats

de Gasparo, Marc, Hess, Patrick, Clozel, Martine, Persohn, Elke, Roman, Danielle, Germann, Paul-Georg, Clozel, Jean-Paul, Webb, Randy L.

Journal:

Journal of Cardiovascular Pharmacology

Year:

2002

Language:

english

File:

PDF, 1.12 MB

english, 2002

33

Protective Effect of Cilazapril on the Cerebral Circulation

Véniant, Murielle, Clozel, Jean-Paul, Kuhn, Herbert, Clozel, Martine

Journal:

Journal of Cardiovascular Pharmacology

Year:

1992

File:

PDF, 3.90 MB

1992

34

Pharmacology of the calcium antagonist mibefradil

Lüscher, Thomas F., Clozel, Jean-Paul, Noll, Georg

Journal:

Journal of Hypertension

Year:

1997

Language:

english

File:

PDF, 422 KB

english, 1997

35

Endothelin Mediates the Altered Renal Hemodynamics Associated with Experimental Congestive Heart Failure

Qiu, Changbin, Ding, Shuang-Shuang, Hess, Patrick, Clozel, Jean-Paul, Clozel, Martine

Journal:

Journal of Cardiovascular Pharmacology

Year:

2001

Language:

english

File:

PDF, 120 KB

english, 2001

36

Discovery and main pharmacological properties of mibefradil (Ro 40-5967), the first selective T-type calcium channel blocker

Clozel, Jean-Paul, Ertel, Eric A., Ertel, Sylvie I.

Journal:

Journal of Hypertension

Year:

1997

Language:

english

File:

PDF, 293 KB

english, 1997

37

Ro 40–5967, in Contrast to Diltiazem, Does Not Reduce Left Ventricular Contractility in Rats with Chronic Myocardial Infarction

Véniant, Murielle, Clozel, Jean-Paul, Hess, Patrick, Wolfgang, Robert

Journal:

Journal of Cardiovascular Pharmacology

Year:

1991

File:

PDF, 437 KB

1991

38

222 Increased lesions in the clipped kidney in two-kidney, one clip rats during angiotensin converting enzyme inhibition is explained by the blood pressure fall

V??niant, M., Clozel, Jean-Paul, M??nard, Jo??l

Journal:

Journal of Hypertension

Year:

1993

File:

PDF, 159 KB

1993

39

Experimental Pulmonary Embolus in the Rat

Clozel, Jean-Paul, Holvoet, Paul, Tschopp, Thomas

Journal:

Journal of Cardiovascular Pharmacology

Year:

1988

File:

PDF, 386 KB

1988

40

Effects of Chronic Therapy with Cilazapril, a New Angiotensin-Converting Enzyme Inhibitor, on Regional Blood Flows in Conscious Spontaneously Hypertensive Rats

Clozel, Jean-Paul, Hefti, Fridolin

Journal:

Journal of Cardiovascular Pharmacology

Year:

1987

File:

PDF, 460 KB

1987

41

A comparison of the effects of renin inhibition and angiotensin converting enzyme inhibition upon bradykinin potentiation

V??niant, Murielle, Clozel, Jean-Paul, Fischli, Walter

Journal:

Journal of Hypertension

Year:

1992

File:

PDF, 411 KB

1992

42

Effects of calcium blockade on end-organ damage in experimental hypertension

Ménard, Joël, Karam, Habib, Véniant, Murielle, Heudes, Didier, Bruneval, Patrick, Clozel, Jean-Paul

Journal:

Journal of Hypertension

Year:

1997

Language:

english

File:

PDF, 280 KB

english, 1997

43

Isoproterenol Impairs the Rat Coronary Vasculature

Roux, Sebastien, Clozel, Jean-Paul, Fischli, Walter, Kuhn, Herbert

Journal:

Journal of Cardiovascular Pharmacology

Year:

1992

File:

PDF, 79 KB

1992

44

Role of Endothelin During Reperfusion After Ischemia in Isolated Perfused Rat Heart

Dagassan, Patrick H., Breu, Volker, Clozel, Martine, Clozel, Jean-Paul

Journal:

Journal of Cardiovascular Pharmacology

Year:

1994

File:

PDF, 3.64 MB

1994

45

Cyclosporin-Induced Hypertension in Marmosets

Clozel, Jean-Paul, Fischli, Walter

Journal:

Journal of Cardiovascular Pharmacology

Year:

1989

File:

PDF, 338 KB

1989

46

Cimetidine inhibits the hypoxia-induced increase in cerebral blood flow in dogs

CLOZEL, JEAN-PAUL, AMEND, PHILIPPE, SAUNIER, CLAUDE, HARTEMANN, DENISE

Journal:

Critical Care Medicine

Year:

1985

File:

PDF, 406 KB

1985

47

Effects of chronic ACE inhibition on cardiac hypertrophy and coronary vascular reserve in spontaneously hypertensive rats with developed hypertension

Clozel, Jean-Paul, Kuhn, Herbert, Hefti, Fridolin

Journal:

Journal of Hypertension

Year:

1989

File:

PDF, 868 KB

1989

48

Structural changes and cyclic GMP content of the aorta after calcium antagonism or angiotensin converting enzyme inhibition in renovascular hypertensive rats

V??niant, Murielle, Gray, Gillian A., Heudes, Didier, M??nard, Jo??l, Clozel, Jean-Paul

Journal:

Journal of Hypertension

Year:

1995

File:

PDF, 680 KB

1995

49

Effects of the blockade of the renin???angiotensin system in cyclosporin-induced hypertension

Clozel, Jean-Paul, Fischli, Walter, M??nard, Jo??l

Journal:

Journal of Hypertension

Year:

1993

File:

PDF, 714 KB

1993

50

39 Similar reduction of neointima formation after vascular injury with renin or angiotensin converting enzyme inhibition in guinea pigs

Clozel, Jean-Paul, Fischli, Walter, Hess, P., Michael, C., Schietinger, K., Baumgartner, H. R.

Journal:

Journal of Hypertension

Year:

1993

File:

PDF, 160 KB

1993

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